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PT-141 Injection
Sexual Health

PT-141 Injection

Desire starts in the brain — not the blood vessels

From $230/mo

Pricing varies by protocol

PT-141 (Bremelanotide) is a melanocortin receptor agonist that works through the central nervous system to enhance sexual desire and arousal. Unlike PDE5 inhibitors, it addresses the desire component of sexual function — making it effective for both men and women. Administered via subcutaneous injection.

Licensed Providers · Lab-Guided · Ongoing Support

Key Benefits
  • Works Through the Brain — Activates melanocortin receptors in the CNS to enhance desire — a fundamentally different mechanism than ED pills.
  • For Men & Women — One of the few sexual health treatments effective for both male and female sexual dysfunction.
  • Enhances Desire — Addresses low libido and hypoactive sexual desire, not just the mechanical aspects of arousal.
  • Subcutaneous Injection — Simple self-injection technique — your provider will guide you through the process.
How It Works
Your provider reviews your labs and health history, then prescribes a personalized protocol. Medication is shipped directly to your door from a licensed 503A pharmacy. Your provider monitors your progress with regular lab work and adjusts your plan as needed.
What to Expect
Most patients begin noticing improvements within the first few weeks of treatment. Your provider will schedule follow-up labs and check-ins to track your progress and optimize your protocol over time.

Who It’s For

This treatment may be right for you if you identify with any of the following:

Low libido (men or women) PDE5 inhibitors haven't helped Desire-based dysfunction Women with HSDD Want a non-hormonal option

Other Sexual Health Options

Explore alternative treatments your provider may recommend

View All Sexual Health Treatments →

Reignite Your Connection

PT-141 addresses desire at its source. Start with a private evaluation today.

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What people ask about PT-141 Injection

How much does PT-141 cost at RenewRx?

PT-141 Injection at RenewRx starts at $230/month. That includes your provider consultation, protocol design, and lab monitoring every 90 days — there is no separate membership fee stacked on top. Final pricing depends on the dose and protocol your clinician prescribes after reviewing your bloodwork.

Is PT-141 FDA-approved?

RenewRx dispenses compounded bremelanotide from a licensed 503A pharmacy. Compounded medications are prepared for an individual patient and are not FDA-approved. The FDA-approved branded version is Vyleesi (bremelanotide, for premenopausal women). This use is also off-label, meaning it's prescribed at your clinician's discretion outside the approved indication. We'd rather tell you that plainly than let you assume otherwise — your provider will walk you through what it means before you start.

How is PT-141 taken?

A subcutaneous injection taken as needed, usually 45 minutes to a few hours before anticipated activity.

How long does PT-141 take to work?

Effects typically begin within 45 minutes to two hours and can last several hours.

What are the side effects of PT-141?

Nausea is the most common and the most common reason people discontinue. Flushing, headache, and transient blood pressure increases can also occur. Not appropriate with uncontrolled high blood pressure or cardiovascular disease.

Do I need bloodwork before starting PT-141?

Yes. Every RenewRx protocol begins with a lab panel reviewed by a licensed provider before anything is prescribed. We won't write a prescription off a questionnaire alone. Labs are rechecked every 90 days so your dose is adjusted to how you're actually responding — not to how you're expected to respond.

PT-141 or sildenafil — which do I need?

They solve different problems. Sildenafil and tadalafil address blood flow. PT-141 acts on desire pathways in the brain. If the mechanics work but the desire isn't there, the blood-flow drugs won't help — and vice versa. Your provider should ask which one you're actually describing.

Do I have to sign a contract or commit to a minimum term?

No contract, and no lock-in. Our protocols are structured as three-month programs because that's the window where the physiology actually shows up — hormone and peptide therapy needs time, plus at least one lab recheck, before anyone can honestly say whether it's working. You're committing to giving the protocol a fair trial, not to a contractual obligation.

Answers reviewed and approved by RenewRx clinical staff. This information is educational and is not medical advice or a substitute for evaluation by a licensed provider. Pricing reflects current protocols and may change.