The gold-standard GLP-1 for medical weight loss
Pricing varies by protocol
The most widely studied GLP-1 receptor agonist for weight management, administered as a simple once-weekly subcutaneous injection. Semaglutide works by mimicking a natural hormone that regulates appetite and blood sugar, helping you eat less without feeling deprived. Compounded by licensed 503A pharmacies with dose titration guided by your provider.
Licensed Providers · Lab-Guided · Ongoing Support
This treatment may be right for you if you identify with any of the following:
Explore alternative treatments your provider may recommend
Take the first step with a clinician-guided evaluation. Personalized protocols, compounded medications, ongoing support.
Take the Weight Loss QuizSemaglutide Injection at RenewRx starts at $149/month. That includes your provider consultation, protocol design, and lab monitoring every 90 days — there is no separate membership fee stacked on top. Final pricing depends on the dose and protocol your clinician prescribes after reviewing your bloodwork.
RenewRx dispenses compounded semaglutide from a licensed 503A pharmacy. Compounded medications are prepared for an individual patient and are not FDA-approved. The FDA-approved branded version is Wegovy and Ozempic. We'd rather tell you that plainly than let you assume otherwise — your provider will walk you through what it means before you start.
A once-weekly subcutaneous injection you administer at home. Your provider starts low and titrates upward over several months to minimize side effects.
Reduced appetite usually appears within the first one to two weeks. Measurable weight loss typically follows within the first month and continues to build over three to six months.
Nausea is the most common, especially after a dose increase, and usually fades as your body adapts. Constipation, diarrhea, and reflux are also common. Serious side effects are uncommon; your provider reviews them before you start. Important: GLP-1 medications carry a boxed warning for thyroid C-cell tumors. They are not appropriate for anyone with a personal or family history of medullary thyroid carcinoma or MEN2. Tell your provider if either applies to you.
Yes. Every RenewRx protocol begins with a lab panel reviewed by a licensed provider before anything is prescribed. We won't write a prescription off a questionnaire alone. Labs are rechecked every 90 days so your dose is adjusted to how you're actually responding — not to how you're expected to respond.
Tirzepatide produced greater average weight loss in trials of the branded drugs, but semaglutide has a longer track record and is less expensive. Neither is universally better. Your labs, medical history, tolerance, and budget decide — which is the conversation you have with your provider.
Most of the benefit fades once you stop, because these therapies manage a condition rather than cure it. That said, the goal isn't to keep you on medication forever — your provider will talk with you about duration, tapering, and what an exit looks like. If a clinic never raises that conversation, ask why.
No contract, and no lock-in. Our protocols are structured as three-month programs because that's the window where the physiology actually shows up — hormone and peptide therapy needs time, plus at least one lab recheck, before anyone can honestly say whether it's working. You're committing to giving the protocol a fair trial, not to a contractual obligation.
Answers reviewed and approved by RenewRx clinical staff. This information is educational and is not medical advice or a substitute for evaluation by a licensed provider. Pricing reflects current protocols and may change.
