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Bioidentical Progesterone
Women's Health

Bioidentical Progesterone

Bioidentical progesterone for hormonal balance

From $99/mo

Pricing varies by protocol

Micronized bioidentical progesterone balances estrogen therapy and supports restful sleep. It is essential for women with an intact uterus who are receiving estrogen, providing critical uterine protection.

Licensed Providers · Lab-Guided · Ongoing Support

Key Benefits
  • Balances Estrogen Safely — Provides essential uterine protection for women on estrogen therapy, reducing the risk of endometrial overgrowth.
  • Promotes Deep Sleep — Acts on GABA receptors in the brain to promote calm, restorative sleep without the grogginess of sleep aids.
  • Calms Anxiety & Mood — Naturally soothes anxiety and stabilizes mood swings associated with hormonal fluctuations.
  • Supports Uterine Health — Maintains a healthy endometrial lining and is a cornerstone of safe, balanced hormone replacement therapy.
How It Works
Your provider reviews your labs and health history, then prescribes a personalized protocol. Medication is shipped directly to your door from a licensed 503A pharmacy. Your provider monitors your progress with regular lab work and adjusts your plan as needed.
What to Expect
Most patients begin noticing improvements within the first few weeks of treatment. Your provider will schedule follow-up labs and check-ins to track your progress and optimize your protocol over time.

Who It's For

Women on Estrogen Therapy Sleep Difficulties Anxiety & Mood Changes Hormonal Shifts Uterine Protection Perimenopause & Menopause

Other Women's Health Options

Explore alternative treatments your provider may recommend

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What people ask about Bioidentical Progesterone

How much does bioidentical progesterone cost at RenewRx?

Bioidentical Progesterone at RenewRx starts at $99/month. That includes your provider consultation, protocol design, and lab monitoring every 90 days — there is no separate membership fee stacked on top. Final pricing depends on the dose and protocol your clinician prescribes after reviewing your bloodwork.

Is bioidentical progesterone FDA-approved?

RenewRx dispenses compounded micronized progesterone from a licensed 503A pharmacy. Compounded medications are prepared for an individual patient and are not FDA-approved. The FDA-approved branded version is Prometrium. We'd rather tell you that plainly than let you assume otherwise — your provider will walk you through what it means before you start.

How is bioidentical progesterone taken?

Usually a nightly oral capsule, sometimes a cream. Taken at night because it commonly causes drowsiness — which many women experience as a benefit.

How long does bioidentical progesterone take to work?

Sleep improvement is often noticed within the first week or two. Cycle regulation and mood effects typically develop over one to three months.

What are the side effects of bioidentical progesterone?

Drowsiness is the most common and is why it's taken at bedtime. Other possible effects include bloating, breast tenderness, and mood changes.

Do I need bloodwork before starting bioidentical progesterone?

Yes. Every RenewRx protocol begins with a lab panel reviewed by a licensed provider before anything is prescribed. We won't write a prescription off a questionnaire alone. Labs are rechecked every 90 days so your dose is adjusted to how you're actually responding — not to how you're expected to respond.

Do I need progesterone if I'm taking estrogen?

If you still have a uterus, yes — this is important. Estrogen without progesterone increases the risk of endometrial cancer. Progesterone protects the uterine lining. Any provider prescribing you estrogen alone while you have a uterus is making a serious error.

What happens if I stop taking bioidentical progesterone?

Most of the benefit fades once you stop, because these therapies manage a condition rather than cure it. That said, the goal isn't to keep you on medication forever — your provider will talk with you about duration, tapering, and what an exit looks like. If a clinic never raises that conversation, ask why.

Do I have to sign a contract or commit to a minimum term?

No contract, and no lock-in. Our protocols are structured as three-month programs because that's the window where the physiology actually shows up — hormone and peptide therapy needs time, plus at least one lab recheck, before anyone can honestly say whether it's working. You're committing to giving the protocol a fair trial, not to a contractual obligation.

Answers reviewed and approved by RenewRx clinical staff. This information is educational and is not medical advice or a substitute for evaluation by a licensed provider. Pricing reflects current protocols and may change.